Hint: Prevention is everything. Smile lines are often the first facial lines to make themselves known—and the hardest to ignore. They frame our expressions, mark moments of joy, and tell the story of a life well lived. Still, many of us wonder: can they actually be softened? The short answer is yes—but with realistic expectations and a smart, layered approach. The Key Takeaways Smile lines—clinically known as nasolabial folds —form as facial volume decreases and skin elastic